Murkowski is anticipated to win the general election in November

In Alaska's open primary for the Senate, which included candidates from all parties, Murkowski placed among the top four vote-getters. The top four will now compete in a general election with ranked choices in November. Murkowski, Republican Kelly Tshibaka, and Democrat Patricia Chesbro are predicted to make it to the November election, according to Media News. The identity of the fourth candidate is unknown. As part of his campaign to rid the GOP of any detractors, Trump made Murkowski one of his top targets during this year's midterm elections.

The senator from Alaska was one of seven members of the upper chamber to find Trump guilty of obstruction of justice following the Capitol uprising last year, but she was the only one to do so while running for reelection this year. Trump supported Kelly Tshibaka, a former administrator for Alaska, to take against Murkowski. Tshibaka, a fervent supporter of the previous president, argues that there are unresolved issues about the 2020 election, which he irrationally claims was "taken" from him. But Murkowski is no electoral slouch, and she has demonstrated the ability to triumph in trying situations.

She famously lost the GOP Senate primary during the 2010 tea party uprising, but she went on to win the regular election by running a write-in campaign that helped Alaskans learn how to spell her name correctly. Since then, she has worked to maintain her reputation as a centrist in the Senate by defying her party's position on matters like abortion and health care — and voting to convict Trump in February 2021.

"A presidential candidate must take an oath promising to diligently carry out their duties as well as to uphold, defend, and preserve the US Constitution before being sworn in. President Trump took an oath to defend the United States and everything we hold dear as the country's elected leader and the commander in chief of our armed forces. He didn't keep that oath, "In a statement defending her vote, she stated. Many observers are unsure of how Alaska's new voting system, which was adopted in a ballot initiative in 2020, will play out in the general election.

The four candidates can be ranked by voters in order of preference. A candidate is declared the winner if they receive an absolute majority of the first-place votes. However, if no candidate receives a majority of the vote, they all lose, and their supporters' second choices are distributed to the remaining candidates. Up until a single candidate wins a majority, the process is repeated. Given the system's emphasis on building a coalition rather than depending only on a base and Murkowski's appeal across ideological lines, it is anticipated that Murkowski will benefit.